Ass. Res. Liu Yongchun         Tel: +86-29-        E-mail: surfbioliu@snnu.edu.cn

Education and Work Experiences：

Ph.D., Xi'an Jiaotong University (2013–2017)

Postdoctoral Fellow, Shaanxi Normal University (2018–2022)

Research Interests：

Controllable protein unfolding

Awards and Honors：

First-Class Science and Technology Award of Shaanxi Provincial Government, 2025

Special-Class Award for Outstanding Scientific and Technological Research Achievements in Higher Education Institutions, Department of Education of Shaanxi Province, 2025

Research Projects as Principal Investigator:

1. National Major Scientific Research Instrument Development Project, Grant No. 22427802, "Research System for Controllable Preparation of Flexible Nanofilms," 2025/01–2029/12, 7,827, RMB 300.

2. General Program of the National Natural Science Foundation of China, Grant No. 52473014, "Design of Selective Antibiofouling Interfaces Based on Protein Aggregates," 2025/01–2028/12, RMB 490,000.

3. Young Scientists Program of the National Natural Science Foundation of China, Grant No. 51903147, "Underwater Biological Adhesives Based on Controllable Protein Unfolding and Aggregation Strategies," 2020/01–2022/12, RMB 260,000.

4. General Key Project of Social Development Field of Shaanxi Provincial Department of Science and Technology, Grant No. 2025SF-YBXM-474, "Design of Temporally and Spatially Matched Functional Coatings for Protein-Based Fusion Devices," 2025/06–2027/05, RMB 80,000.

5. Second-Class General Grant of the China Postdoctoral Science Foundation, Grant No. 2019M653864XB, "Development of Onion-like Amyloid Protein Coating for Urinary Catheters," 2019/01–2024/01, RMB 80,000.

Representative Achievements:

1. Li, M.; Zhang, Y.; Liu, Y.; Wang, J.; Zhang, M.; Miao, S.; Tian, J.; Tao, F.; Tian, L.; Li, K.; Yang, P. Redox-Triggered Autologous Protein Assembly for Blood-Contacting Interfaces. ACS Appl. Mater. Interfaces 2026, 18, 14787–14802.

2. Li, L.; Zhang, M.; Wang, J.; Wu, Y.; Tian, L.; Zhang, J.; Chen, H.; Liu, Y.; Yang, P. Bionic Phase-Transitioned α-Lactalbumin Coating for Efficient Separation of Structurally Similar Environmental Endocrine Disruptors by Open Tubular Capillary Electrochromatography. J. Chromatogr. A 2026, 1783, 467121.

3. Zhang, Y.; Ren, H.; Linghu, C.; Zhang, J.; Gao, A.; Su, H.; Miao, S.; Qing, R.; Hu, B.; Chen, X.; Deng, M.; Liu, Y.; Yang, P. Stabilizing Metal Coating on Flexible Devices by Ultra-thin Protein Nanofilms. Adv. Mater. 2024, 36, 2412378.

4. Zhang, M.; Li, K.; Kou, J.; Lu, G.; Qiu, L.; Yang, C.; Liu, Y.; Xue, Q.; Yang, P. Functionalized Amyloid-like Protein Nanofilm Mediated Synergistic Disulfidptosis and Photodynamic Therapy for Preventing Postoperative Recurrence of Colorectal Cancer. Small Sci. 2024, 4, 2400323.

5. Niu, T.; Mao, Y.; Lv, Y.; Li, M.; Liu, Y.; Yang, P.; Gu, Q. Amyloid-Like Protein-Modified Carbon Nitride as a Bioinspired Material for Enhanced Photocatalytic CO2 Reduction. ACS Appl. Mater. Interfaces 2024, 16, 63495–63508.

6. Pang, Y.; Fu, C.; Zhang, D.; Li, M.; Zhou, X.; Gao, Y.; Lin, K.; Hu, B.; Zhang, K.; Cai, Q.; Yang, P.; Liu, Y.; Zhang, X. Biomimetic Remineralization of Dental Hard Tissues via Amyloid-Like Protein Matrix Composite with Amorphous Calcium Phosphate. Adv. Funct. Mater. 2024, 2403233.

7. Li, L.; Zhang, Y.; Wu, Y.; Wang, Z.; Cui, W.; Zhang, C.; Wang, J.; Liu, Y.; Yang, P. Protein-Based Controllable Nanoarchitectonics for Desired Applications. Adv. Funct. Mater. 2024, 2315509.

8. Liu, Y.; Miao, S.; Ren, H.; Tian, L.; Zhao, J.; Yang, P. Synthesis and Regulation of Versatile 2D Protein Films by Amyloid-Like Aggregation. Nat. Protoc. 2024, 19, 539–564.

9. Liu, Y.; Li, K.; Tian, J.; Gao, A.; Tian, L.; Su, H.; Miao, S.; Tao, F.; Ren, H.; Yang, Q.; Cao, J.; Yang, P. Synthesis of Robust Underwater Glues from Common Proteins via Unfolding-Aggregating Strategy. Nat. Commun. 2023, 14, 5145.

10. Gao, Y.; Pang, Y.; Wei, S.; Han, Q.; Miao, S.; Li, M.; Tian, J.; Fu, C.; Wang, Z.; Zhang, X.; Yang, P.; Liu, Y. Amyloid-Mediated Nanoarchitectonics with Biomimetic Mineralization of Polyetheretherketone for Enhanced Osseointegration. ACS Appl. Mater. Interfaces 2023, 15, 10426–10440.

11. Zhang, Y.; Liu, Y.; Liu, Y.; Zuo, P.; Miao, S.; Hu, B.; Kang, Y.; Liu, W.; Yang, Q.; Ren, H.; Yang, P. α-Helix-Mediated Protein Adhesion. J. Am. Chem. Soc. 2023, 145, 17125–17135.

12. Su, H.; Liu, Y.; Gao, Y.; Fu, C.; Li, C.; Qin, R.; Liang, L.; Yang, P. Amyloid-Like Protein Aggregation Toward Pesticide Reduction. Adv. Sci. 2022, 9, 2105106.

13. Zhang, C.; Jiang, X.; Yu, F.; Liu, Y.; Yue, Q.; Yang, P.; Liu, Y. Antagonistic Action Regulated Anti-Etching Colorimetric Detection of Thiram Residue in Soil Based on Triangular Silver Nanoplates. Sens. Actuators, B 2021, 344, 130304.

14. Liu, Y.; Tao, F.; Miao, S.; Yang, P. Controlling the Structure and Function of Protein Thin Films through Amyloid-like Aggregation. Acc. Chem. Res. 2021, 54, 3016–3027.

15. Yan, X.; Liu, Y.; Hu, X.; Qin, R.; Su, H.; Li, J.; Yang, P. The Synthesis of a 2D Ultralarge Protein Supramolecular Nanofilm by Chemoselective Thiol-Disulfide Exchange and its Emergent Functions. Angew. Chem., Int. Ed. 2020, 59, 2850–2859.