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Prof. Wang Changhao E-mail: changhaowang@snnu.edu.cn |
Educations and Work Experiences:
Professor, Shaanxi Normal University (2021.01 to present)
Associate Professor, Shaanxi Normal University (2017.07 to 2020.12)
Postdoc, University of Konstanz, Germany (2015.04-2017.06)
Postdoc, University of Maryland C United States (2013.11-2015.02)
PhD, Dalian Institute of Chemical Physics, Chinese Academic of Sciences (2006.08-2013.10)
Awards and Honors:
Second Prize in National Teaching Competition for Young University Faculty, 2023
Grand Prize in Shaanxi Provincial Teaching Competition for Young University Faculty, 2023
Research Projects as Principal Investigator:
1. National Natural Science Foundation of China - Excellent Young Scientists Fund
Grant No. 22222203, "Nucleic Acids Catalytic Chemistry", January 2023-December 2025, RMB 2 million.
2. National Natural Science Foundation of China - General Program
Grant No. 22572111, "Construction of dual-active-site DNA hybrid catalysts and their structure-activity relationship in enantioselective catalysis", January 2026-December 2029, RMB 500,000.
3. National Natural Science Foundation of China - General Program
Grant No. 22072080, "Studies on the host-guest interaction of cyclic RNA-based artificial metalloribozymes and their structure-activity relationship in enantioselective catalysis", January 2021-December 2024, RMB 630,000.
4. National Natural Science Foundation of China-Young Scientists Fund
Grant No. 21703132, "Studies on the enantioselective catalytic functions of c-di-GMP", January 2018-December 2020, RMB 240,000.
5. Shaanxi Provincial Natural Science Foundation-Key Program
Grant No. 2025JC-QYCX-014, "Precise Regulation and Catalytic Structure-Activity Relationships of Functionalized DNA Catalysts", January 2025-December 2027, RMB 200,000
Representative Publications:
[1] Min Fan, Changhao Wang*, Hengquan Yang*, Co-confinement of enzymes and cofactors within Pickering droplet derived microreactors for continuous flow catalysis. Angew. Chem. Int. Ed., 2026, 65, e25681.
[2] Xingchen Dong, Weijun Qin, Zixiao Wang, Wenqin Zhou, Shanmei Xu, Mengyao Wang, Jin Zhang, Linna Wang, Guoqing Jia, Yashao Chen, Changhao Wang*, H+/Ag+ switch of enantioselectivity in i-motif DNA-based Friedel-Crafts reactions. J. Am. Chem. Soc., 2026, 148, 6462-6473.
[3] Xingchen Dong,# Ziyang Qiu,# Zixiao Wang, Jiaqi Li, Weijun Qin, Jingshuang Dang, Wenqin Zhou, Guoqing Jia, Yashao Chen, Changhao Wang*, Efficient silver(I)-containing i-motif DNA hybrid catalyst for enantioselective Diels–Alder reactions. Angew. Chem. Int. Ed., 2024, 63, e202407838. (# equal author)
[4] Weijun Qin,# Zixiao Wang,# Xingchen Dong, Zhaohui Wang, Yashao Chen, Changhao Wang*, Research progress of nucleic acids based asymmetric catalysis. Sci. Sin. Chim., 2024, 54, 1727-1743 (# equal author)
[5] Changhao Wang,#,* Qianqian Qi,# Wenying Li, Jingshuang Dang, Min Hao, Shuting Lv, Xingchen Dong, Youkun Gu, Peizhe Wu, Wenyue Zhang, Yashao Chen, Jörg S. Hartig, A Cu(II)-ATP complex efficiently catalyses enantioselective Diels-Alder reactions. Nat. Commun., 2020, 11, 4792. (# equal author)
[6] Changhao Wang,#,* Min Hao,# Qianqian Qi, Jingshuang Dang, Xingchen Dong, Shuting Lv, Ling Xiong, Huanhuan Gao, Guoqing Jia, Yashao Chen*, Jörg S. Hartig, Can Li, Highly efficient cyclic dinucleotide based artificial metalloribozymes for enantioselective Friedel-Crafts reactions in water. Angew. Chem. Int. Ed., 2020, 59, 3444-3449. (# equal author)