Prof.  Yang Jun    Tel: 18792597973  E-mail:junyang@snnu.edu.cn

Education and Work Experiences：

PhD., Sichuan University, (2008)

Assistant Researcher，Scripps Research Institute, San Diego, (USA), (2008-2011)

Post-Doc, University of California, San Diego, (USA), (2011-2013)

Research Interests：

Natural product synthesis

Medicinal chemistry

Chemicobiology

Awards and Honors：

National 100 Excellent Doctoral Thesis Award, 2010

Research Projects as Principal Investigator：

1. Technology Development Project, Grant No. 2025239, “Synthesis Research of Bifunctional Chelator H3RESCA and THP”, December 2025-December 2026, RMB 0.3 million.

2. Technology Development Project, Grant No. 2024105, “Research on Synthesis of Hetero-modified Dispersed PEG and Dendritic PEG”, July 2024-July 2027, RMB 0.3 million.

3. Technology Development Project, Grant No. 2025096, “Click Chemical Small Molecule Probe Synthesis Process Research 2025”, June 2025-June 2028, RMB 0.3 million.

4. Technology Development Project, Grant No. 2024106, “Series Click Chemical Probe and Fluorescent Dye Synthesis Research”, July 2024-July 2027, RMB 0.3 million.

5. Technology Development Project, Grant No. 2021101, “DOTA, NOTA Bifunctional Chelating Agent Synthesis Process Research”, September 2021-September 2023, RMB 0.2 million.

6. Technology Development Project, Grant No. 2019130, “Click Chemical Small Molecule Probe Synthesis Process Research”,  December 2019-December 2024, RMB 2 million.

Representative Achievements：

1．H. X. Wu¹, Jun Yang¹,‎ J. Seckute, N. K. Devaraj*. In Situ Synthesis of Alkenyl Tetrazines for Highly Fluorogenic Bioorthogonal Live-Cell Imaging Probes. Angew. Chem. Int. Ed., 2014, 53, 5805-5809.

2．M. L. Gou, X. Qu, W. Zhu, M. Xiang, Jun Yang, K. Zhang, Y. Wei, and S.C. Chen, "Bio-inspired Detoxification using 3D-printed Hydrogel Nanocomposites”, Nature Communications, 2014,5, 3774.

3．Jun Yang¹, Y. Liang¹, J. Seckute, K. N. Houk*, N. K. Devaraj*. Synthesis and Reactivity Comparisons of 1-Methyl-3-Substituted Cyclopropene Mini-Tags for Tetrazine Bioorthogonal Reactions. Chem. Eur. J., 2014,20, 3365–3375.

4．C. M. Cole¹, Jun Yang¹, J. Seckute, N. K. Devaraj*. Fluorescent Live-Cell Imaging of Metabolically Incorporated Unnatural Cyclopropene Mannosamine Derivatives. ChemBioChem., 2013, 14(2), 205-208.

5．Jun Yang, J. Šečkutė, C. M. Cole, N. K. Devaraj*. Live-Cell Imaging of Cyclopropene Tags with Fluorogenic Tetrazine Cycloadditions. Angew. Chem. Int. Ed., 2012, 51, 7476-7479.

6．Jun Yang, Mark Karver, Weilong Li, Swagat Sahu, Neal K. Devaraj*. Metal-Catalyzed One-Pot Synthesis of Tetrazines Directly from Aliphatic Nitriles and Hydrazine. Angew. Chem. Int. Ed., 2012, 51, 5222 –5225.

7．Jun Yang, Haoxin Wu, Liqun Shen, Yong Qin. Total Synthesis of (±)-Communesin F. J. Am. Chem. Soc., 2007,129, 13794-13795.

8．Jun Yang, Hao Song, Xue Xiao, Jue Wang, Yong Qin. Biomimetic Approach to Perophoramidine and Communesin Via an Intramolecular Cyclopropanation Reaction. Org. Lett., 2006,8, 2187.