代表性成果

1. 创新发展了基于单微球的分析新策略

2. 发展了新型核酸扩增体系

3. 制备了系列磷酸化肽识别微纳新材料

近期发表论文情况：

1. Liying Qiu, Yuecheng Zhang, Chenghui Liu*, Zhengping Li*. A Versatile Size-Coded Flow Cytometric Bead Assay for Simultaneous Detection of Multiple MicroRNAs Coupled with a Two-Step Cascading Signal Amplification. Chem. Commun., 2017, 53, 2926-2929.

2. Xiangdong Wang, Hui Wang, Chenghui Liu*, Honghong Wang, Zhengping Li*. A three-way junction structure-based isothermal exponential amplification strategy for sensitive detection of 3’-terminal 2’-O-methylated plant microRNA. Chem. Commun., 2017, 53, 1124-1127.

3. Hui Tian, Yuanyuan Sun, Chenghui Liu*, Xinrui Duan, Wei Tang, Zhengping Li*. Precise Quantitation of MicroRNA in a Single Cell with Droplet Digital PCR Based on Ligation Reaction. Anal. Chem., 2016, 88, 11384−11389.

4. Junting Li, Qi Zhao, Feng Shi, Chenghui Liu*, Yanli Tang*. NIR-Mediated Nanohybrids of Upconversion Nanophosphors and Fluorescent Conjugated Polymers for High-Efficiency Antibacterial Performance Based on Fluorescence Resonance Energy Transfer. Adv. Healthcare Mater., 2016, 5, 2967-2971. (Highlighted by MaterialsViewsChina)

5. Chao Jiang, Ya Li, Chenghui Liu*, Liying Qiu, Zhengping Li. A General and Versatile Fluorescence Turn-On Assay for Detecting the Activity of Protein Tyrosine Kinases Based on Phosphorylation-Inhibited Tyrosyl Oxidation. Chem. Commun., 2016, 52, 12570-12573. (Front Cover)

6. Honghong Wang, Hui Wang, Chenghui Liu,* Xinrui Duan, Zhengping Li.* Ultrasensitive Detection of Telomerase Activity in a Single Cell Using Stem-loop Primer-mediated Exponential Amplification (SPEA) with Near Zero Nonspecific Signal. Chem. Sci., 2016, 7, 4945-4950.

7. Xiaohui Lu, Peipei Wang, Yucong Wang*, Chenghui Liu,* Zhengping Li. A Versatile Dual-Emission Fluorescent Microhybrid Enabling Visual Detection of Glucose and Other Oxidases-Based Biocatalytic Systems. Adv. Mater. Technol., 2016, 1, 1600024. (Inside Front Cover, Highlighted by MaterialsViewsChina)

8. Xiaobo Zhang, Chenghui Liu*, Honghong Wang, Hui Wang, Zhengping Li*. Rare Earth Ion Mediated Fluorescence Accumulation on a Single Microbead: An Ultrasensitive Strategy for the Detection of Protein Kinase Activity at the Single-Cell Level. Angew. Chem. Int. Ed., 2015, 54, 15186-15190.

9. Xiaobo Zhang, Chenghui Liu*, Lingbo Sun, Xinrui Duan, Zhengping Li*. Lab on a single microbead: an ultrasensitive detection strategy enabling microRNA analysis at the single-molecule level. Chem. Sci., 2015, 6, 6213-6218. (Hot article of Chemical Science; Highlighted by Chemistry World).

10. Yuecheng Zhang, Chenghui Liu,* Sujuan Sun, Yanli Tang, Zhengping Li.* Phosphorylation-Induced Hybridization Chain Reaction on Beads: An Ultrasensitive Flow Cytometric Assay for the Detection of T4 Polynucleotide Kinase Activity. Chem. Commun., 2015, 51, 5832-5835. (Front Inside Cover)