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王长号

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王长号    教授

Assoc. Prof. Changhao Wang

E-mail: changhaowang@snnu.edu.cn

学习及工作经历(从博士开始):

陕西师范大学(中国)副教授(2017.07-至今)

康斯坦茨大学(德国)博士后 (2015.04-2017.06)

马里兰大学帕克分校(美国)博士后 (2013.11-2015.02)

中国科学院大连化学物理研究所(中国)博士(2006.08-2013.10

Educations and Work Experiences

Assoc. Prof., Shaanxi Normal University (2017.07 to present)

       Postdoc, University of Konstanz, Germany (2015.04-2017.06)

       Postdoc, University of Maryland, College Park, United States (2013.11-2015.02)

       PhD, Dalian Institute of Chemical Physics, Chinese Academic of Sciences (2006.08-2013.10)

奖励及荣誉:

中国科学院院长奖-优秀奖(2013

林励吾催化奖-优秀博士生奖(2012

Awards and Honors

Excellence Award of President of Chinese Academy of Sciences (2013)

Lin Liwu Catalysis Award: Outstanding Doctor Scholarship (2012)

研究领域:

核酸的催化功能

生物医用材料的表界面化学

Research interests:

Catalytic functions of nucleic acids

Surface & interface chemistry of biomedical materials

代表性成果(Representative Publications,包括论文、专利、著作等)

(1) Chemical synthesis, purification, and characterization of 3’-5’-linked canonical cyclic dinucleotides (CDNs).

Changhao Wang*, Min Hao, Qianqian Qi, Yashao Chen, Jörg S. Hartig*, Methods in Enzymology, 2019, DOI: https://doi.org/10.1016/bs.mie.2019.04.022.

(2) Fabrication of PMPC/PTM/PEGDA micropatterns onto polypropylene films behaving with dual functions of antifouling and antimicrobial activities.

Liu Jiang, Wancheng Zhu, Huaming Qian, Changhao Wang*, Yashao Chen*, Peng Liu*, Journal of Materials Chemistry B, 2019, DOI: 10.1039/C9TB00927B.

(3) Synthesis of all possible canonical (3´-5´-linked) cyclic dinucleotides and evaluation of riboswitch interactions and immune-stimulatory effects.

Changhao Wang, Malte Sinn, Julia Stifel, Anna C. Heiler, Annette Sommershof, Jörg S. Hartig*, Journal of the American Chemical Society, 2017, 139, 16154-16160.

(4) Alkyne-substituted diminazene as G-quadruplex binders with anticancer activities.

Changhao Wang, Brandon Carter-Cooper, Yixuan Du, Jie Zhou, Musabbir A. Saeed, Jinbing Liu, Min Guo, Benjamin Roembke, Clinton Mikek, Edwin A. Lewis, Rena G. Lapidus, Herman O. Sintim*, European Journal of Medicinal Chemistry, 2016, 18, 266-275.

(5) Na+/K+ switch of enantioselectivity in G-quadruplex DNA-based catalysis.

Changhao Wang, Guoqing Jia, Yinghao Li, Sufang Zhang, Can Li*, Chemical Communications, 2013, 49, 11161-11163.

(6) Enantioselective Friedel−Crafts reaction in water catalyzed by a human telomeric G-quadruplex DNA metalloenzyme.

Changhao Wang, Yinghao Li, Guoqing Jia, Yan Liu, Shengmei Lu, Can Li*, Chemical Communications, 2012, 48, 6232-6234.

(7) Enantioselective Diels−Alder reaction with G-quadruplex DNA-based catalysts.

Changhao Wang, Guoqing Jia, Jun Zhou, Yinghao Li, Yan Liu, Shengmei Lu, Can Li*, Angewandte Chemie International Edition, 2012, 51, 9352-9355.